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sema3a inhibitor sm345431  (MedChemExpress)


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    Structured Review

    MedChemExpress sema3a inhibitor sm345431
    Sema3a Inhibitor Sm345431, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sema3a+inhibitor+sm345431/Vinaxanthone/pm41981450-153-20-25
    Average 94 stars, based on 5 article reviews
    sema3a inhibitor sm345431 - by Bioz Stars, 2026-09
    94/100 stars

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    Article Title: Multifunctional ions/drugs co-delivering nanocomposite hydrogel orchestrates neuro-osteogenic microenvironment for boosting osteoporotic osseointegration.
    Article Snippet: Likewise, semaphorin secretions of DRG co-cultured in materials extracts for 7 days were examined by using antibodies against Sema3A (Santa Cruz, USA), Sema3E (Thermo, USA), Sema4D (Santa Cruz, USA), Sema7A (Santa Cruz, USA) and GAPDH (Abcam, UK). .. To investigate the key signaling molecules responsible for neuro-inductive osteogenesis of Gel/P@SrZn-MSNs/G, the medium of co-cultured BMSCs were supplemented with/without Sema3A inhibitor SM345431 (2 μM, MedChemExpress, USA) or Wnt/β-catenin inhibitor XAV939 (10 μM, Selleckchem, USA) for 7 days, then western blot assays were performed by using antibodies against Nrp1 (Affinity, USA), p-Rac1 (Affinity, USA), Rac1 (Affinity, USA), Wnt6 (Abcam, UK), β-catenin (Abcam, UK), ALP (Abcam, UK), Runx2 (Abcam, UK) and GAPDH (Abcam, UK). .. The expressed protein bands were detected by a chemiluminescence device (Beyotime, China) and then analyzed for gray values (n = 4) by using AlphaEaseFC software.



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